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Case 20. Giardiasis
(30 y-o M)
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| Duodenal biopsy from an Iranian male complaining of abdominal discomfort and mild diarrhea | |||||
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Key words :
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Giardia lamblia, lymphoid hyperplasia, intraepithellial lymphocyte, cholecystitis | ||||
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zoonosis
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| Chronic active duodenitis with lymphoid follicle formation (HE) | Chronic active duodenitis with increased intraepithelial lymphocytes and surface infection of G. lamblia (HE) | |
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| Trophozoites of G. lamblia seen in the lumen of the duodenal mucosa (HE, high power) | Distribution of CD3-positive T-cells in the duodenal mucosa showing marked increase of intraepithelial lymphocytes (immunostaining) | |
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| The intraepithelial lymphocytes are predominantly positive for CD8, a marker of killer T-cells (immunostaining). | CD79a-positive B-cells are seen in the lymphoid follicle, in association with focal intraepithelial clustering (immunostaining). | |
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| Reference case 20A Trophozoites of Giardia lamblia seen in bile. Flagellated and binucleated giardial trophozoites are co-infected with bacteria in the gallbladder (Giemsa). |
Reference case 20A Trophozoites of Giardia lamblia seen in bile. Binucleated giardial trophozoites in the bile (Papanicolaou). |
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