Case 106. Naegleria meningoencephalitis (26 y-o M)

　 　 　 　
　
Lethal acute meningoencephalitis menifesting 1 week after diving into fresh water
 　
　 　 　 　

　

 　 Macrophage-like trophozoites of Naegleria fowleri are clustered around small vessels in the Virchow-Robin space (HE). The lesion extends in a centripetal fashion from the subarachnoid space into the cerebral cortex.