Case 106. Naegleria meningoencephalitis (26 y-o M)

　 　 　 　
　
Lethal acute meningoencephalitis menifesting 1 week after diving into fresh water
 　
　 　 　 　

　

 　 Numbers of macrophage-like trophozoites with eosinophilic vacuolated cytoplasm are clustered around small vessels near the brain surface (HE). Cysts are not formed in the lesion.