Case 106. Naegleria meningoencephalitis (26 y-o M)

　 　 　 　
　
Lethal acute meningoencephalitis menifesting 1 week after diving into fresh water
 　
　 　 　 　

　

 　 Oil immersion observation of the trophozoites in the Virchow-Robin space discloses the vacuolated cytoplasm and a single nucleus with centally located (target-like) karyosome.