Case 117. VZV encephalitis in AIDS (40 y-o M)

       
 
Fatal necrotizing encephalitis manifested after healing of herpes zoster
 
       

 

  Intranuclear inclusions, Cowdry's type A, are formed in neurons located in the edematous neuropil background (HE). Histologic features of VZV encephalitis are indistinguishable from those of HSV encephalitis.