Case 119. 

Measles encephalitis (subacute sclerosing panencephalitis) (8 y-o M)
　 　 　 　
　 Brain lesion featured by progressive mental retardation and myoclonus (history of measles in infancy) 　
　 　 　 　

　

 　 The disease SSPE is featured by inflammatory demyelination and gliosis in the white matter of the brain. Astrocytic gliosis and vacuolar degeneration of neuropil are observed (HE). Neuronophagia is mildly seen in the gray matter.