Case 125. Acanthamebic meningoencephalitis (60 y-o M)

　 　 　 　
　 Brain biopsy from highly edematous right hemisphere in case of alcoholic liver cirrhosis manifesting left hemiparesis (HIV: negative) 　
　 　 　 　

　

 　 Some of the large round cells around small vessels, resembling macrophages, possess round nuclei with central karyosome, a characteristic microscopic feature of protozoa (HE, high power).