Case 125. Acanthamebic meningoencephalitis (60 y-o M)

       
  Brain biopsy from highly edematous right hemisphere in case of alcoholic liver cirrhosis manifesting left hemiparesis (HIV: negative)  
       

 

  The 1:1,000 diluted patient's own serum stains the amebic cells and the cytoplasm of macrophages phagocytizing the amebic antigens (indirect immunoperoxidase). Serologic study confirmed a high titer against A. culbertsoni.