Case 127. Microsporidiosis (22 y-o M)

　 　 　 　
　 Biopsied multifocal white matter lesions, up to 1 cm in size, seen in an HIV-negative patient who often eats raw cow liver 　
　 　 　 　

　

 　 A necrotic lesion with dense infiltration of lymphoid cells and macrophages is presented. In the cytoplasm of glial cells, basophilic granules are observed infrequently (HE).