Case 127. Microsporidiosis (22 y-o M)

　 　 　 　
　 Biopsied multifocal white matter lesions, up to 1 cm in size, seen in an HIV-negative patient who often eats raw cow liver 　
　 　 　 　

　

 　 The basophilic short rods are focally clustered within a cytoplasmic vacuole in the other astrocyte (HE, oil immersion). Microsporidiosis, probably infection of Encephalitozoon sp., is strongly suspected.