Case 176. Reference case 176A

　 　 　 　
　 Numerous amastigotes are phagocytized by macrophages in the dermis (HE). PAS and Grocott stains are negative. 　
　 　 　 　

　

 　 The number of protozoa in the lesion is dependent on the timing of biopsy. In the old regressing lesion, fewer pathogens are seen in granulomatous reactions.