Case 206. Malaria falciparum (60 y-o M)

　 　 　 　
　 Japanese photographer who traveled in Kenya, menifesting high fever, jaundice and consciouness disturbance (Refer to case 129, the same case) 　
　 　 　 　

　

 　 The liver tissue at autopsy exhibits stasis of red cells containing coarse malaria pigment in the sinusoid, and activation of Kupffer cells, phagocytizing the infected red cells (Giemsa). In case of falciparum malaria, the red cells infected by trophozoites and schizonts are trapped to the endothelial cells via CD36 and ICAM-I, so that these cells are not seen in the peripheral blood.