Case 218. HIV-associated lymphadenopathy (32 y-o M)

　 　 　 　
　 Biopsied cervical lymph node in an HIV carrier without any opportunistic infection 　
　 　 　 　

　

 　 Moth-eaten appearance of the enlarged germinal center (folliculolysis) is demonstrated by silver impregnation. This phenomenon is caused by HIV-induced destruction of CD21- or CD35-positive follicular dendritic cells.